P4 cap modified tetrapeptidyl α-ketoamides as potent HCV NS3 protease inhibitors

…, B Heinz, A Kolykhalov, J Lamar, RB Johnson…

文献索引：Sun, David X.; Liu, Lifei; Heinz, Beverly; Kolykhalov, Alexander; Lamar, Jason; Johnson, Robert B.; Wang, Q. May; Yip, Yvonne; Chen, Shu-Hui Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 16 p. 4333 - 4338

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被引用次数: 24

摘要

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... We describe herein the design, syntheses, and biological evaluation of new series of P4 tetrazole and adipic acid, ester, amide capped tetrapeptidyl α-ketoamide based HCV protease inhibitors. ... The design, syntheses, and biological evaluation of new series of P4 tetrazole, adipic acid, ...