Synthetic communications

A Highly Practical Route to 7-Hydroxy-1, 3-dihydro-2 H-1, 4-benzodiazepin-2-one from p-Anisidine

C Wu, RJ Biediger, TP Kogan

文献索引：Wu, Chengde; Biediger, Ronald J.; Kogan, Timothy P. Synthetic Communications, 1999 , vol. 29, # 20 p. 3509 - 3516

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被引用次数: 4

摘要

Chengde Wu,* Ronald J. Biediger, and Timothy P. Kogan ... Texas Biotechnology Corporation 7000 Fannin, Suite 1920, Houston, Texas 77030 ... Abstract: The title compound was accessed via a Friedel-Crafts reaction on anisidine, followed by cyclization, N-methylation and 0-demethylation. NO column chromatography was required in the process. ... Upon screening a combinatorid library of 7-hydroxy- 1 ,Cbenzodiazepines ... * To whom correspondence ...