Engineered biosynthesis of plant polyketides: chain length control in an octaketide-producing plant type III polyketide synthase

I Abe, S Oguro, Y Utsumi, Y Sano…

文献索引：Abe, Ikuro; Oguro, Satoshi; Utsumi, Yoriko; Sano, Yukie; Noguchi, Hiroshi Journal of the American Chemical Society, 2005 , vol. 127, # 36 p. 12709 - 12716

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被引用次数: 114

摘要

The chalcone synthase (CHS) superfamily of type III polyketide synthases (PKSs) produces a variety of plant secondary metabolites with remarkable structural diversity and biological activities (eg, chalcones, stilbenes, benzophenones, acrydones, phloroglucinols, resorcinols, pyrones, and chromones). Here we describe an octaketide-producing novel plant-specific type III PKS from aloe (Aloe arborescens) sharing 50-60% amino acid ...