Acta Chem. Scand

Synthesis of DL-Statine and DL-4-Amino-3-hydroxy-4-phenylbutanoic acids via the isoxazoline route

K Hallig, KBG Torssell, RG Hazell

文献索引：Halling, Karen; Torssell, Kurt B. G.; Hazell, Rita G. Acta Chemica Scandinavica, 1991 , vol. 45, # 7 p. 736 - 741

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被引用次数: 15

摘要

1, 3-Dipolar cycloaddition of chloronitrile oxide to N-allyltrichloroacétamides and subsequent reductive cleavage of the 3-methoxy-substituted isoxazolines gives methyl 3- hydroxy-4-trichloroacetamido esters which by acidic hydrolysis give the corresponding