Improved Synthesis of Fluoromethyl Phenyl Sulfone

DP Matthews, RA Persichetti…

文献索引：Matthews, Donald P.; Persichetti, Rose A.; McCarthy, James R. Organic Preparations and Procedures International, 1994 , vol. 26, # 5 p. 605 - 608

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被引用次数: 6

摘要

We recently reported a synthesis of fluoromethyl phenyl sulfone (4) using the “fluoro- Pummerer” synthesis which employs diethylaminosulfur trifluoride (DAST) as the fluoride sourcc. I Compound 4 is an important starting material which we have used for the stereospecific synthesis of terminal vinyl fluoridcs. 2, 3 In addition, this methodology has been applied to the synthesis of