Stereoselective synthesis of N-alkylaziridines from N-chloroamines

…, DL Hughes, NJ Palmer, V Savic, KM Soapi…

文献索引：Bew, Sean P.; Hughes; Palmer, Nicholas J.; Savic, Vladimir; Soapi, Katy M.; Wilson, Martin A. Chemical Communications, 2006 , # 41 p. 4338 - 4340

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被引用次数: 3

摘要

The development of protocols that afford difficult to synthesise N-alkylaziridines is a challenge yet to be addressed. 1 In this Communication we report that N-chloroamines can be used for the efficient synthesis of N-alkylaziridines. Our results demonstrate that, contrary to literature precedent, N-chloroamines are relatively stable, efficient, readily accessible starting materials that afford structurally diverse N-alkylaziridines that would, using conventional protocols, ...