Phosphane ligands with two binding sites of differing hardness for enantioselective Grignard cross coupling

A Terfort, H Brunner

文献索引：Terfort, Andreas; Brunner, Henri Journal of the Chemical Society - Perkin Transactions 1, 1996 , # 12 p. 1467 - 1479

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被引用次数: 38

摘要

A series of new, chiral phosphanes is presented, individual members of which were designed to serve as ligands in transition-metal mediated asymmetric Grignard cross coupling reactions. These ligands are characterized by a side chain containing one or two oxygen atoms with the capacity to act as binding sites for the incoming Grignard reagent. A number of structural parameters for the compounds was varied to learn about the reaction ...