Tetrahedron letters

An efficient protocol for a sharpless style racemic dihydroxylation

J Eames, HJ Mitchell, A Nelson, P O'Brien, S Warren…

文献索引：Eames, Jason; Mitchell, Helen J.; Nelson, Adam; O'Brien, Peter; Warren, Stuart; Wyatt, Paul Tetrahedron Letters, 1995 , vol. 36, # 10 p. 1719 - 1722

全文：HTML全文

被引用次数: 33

摘要

Dihydroxylation with solid OsCl3 to provide the catalytic oxidant, K3Fe (CN) 6 as stoichiometric oxidant, quinuclidine as the accelerating ligand with added K2CO3 and methanesulfonamide in a two-phase system (water and t-butanol) gives excellent yields of racemic syn diols from various alkenes (stilbenes, sulfides and phosphine oxides).