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Analysis of Dopamine and Tyrosinase Activity on Ion??Sensitive Field??Effect Transistor (ISFET) Devices

R Freeman, J Elbaz, R Gill, M Zayats…

文献索引:Freeman, Ronit; Elbaz, Johann; Gill, Ron; Zayats, Maya; Willner, Itamar Chemistry - A European Journal, 2007 , vol. 13, # 26 p. 7288 - 7293

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被引用次数: 34

摘要

Abstract Dopamine (1) and tyrosinase (TR) activities were analyzed by using chemically modified ion-sensitive field-effect transistor (ISFET) devices. In one configuration, a phenylboronic acid functionalized ISFET was used to analyze 1 or TR. The formation of the boronate–1 complex on the surface of the gate altered the electrical potential associated with the gate, and thus enabled 1 to be analyzed with a detection limit of 7× 10− 5 M. ...