Chemistry and hypoglycemic activity of N-[[(dialkylamino) alkoxy] phenyl] benzamidines

…, B Elpern, S Kobrin, P Cervoni

文献索引：Shroff; Elpern; Kobrin; Cervoni Journal of Medicinal Chemistry, 1982 , vol. 25, # 4 p. 359 - 362

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被引用次数: 3

摘要

Method A. The benzamidines were prepared by allowing the substituted benzimidoyl chlorides to react with [(dialkylamino) alkoxy] anilines. The resulting benzamidine hydrochlorides were converted to the free base by treatment with ammonium hydroxide. The base was then converted to the desired addition salts. The intermediate benzimidoyl chlorides were prepared from the corresponding N-substituted benzamides by treatment ...