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Synthesis of novel 2-alkyl-4-substituted-amino-pyrazolo [3, 4-d] pyrimidines as new leads for anti-bacterial and anti-cancer activity

M Devarakonda, R Doonaboina, S Vanga…

文献索引:Devarakonda, Murty; Doonaboina, Raghava; Vanga, Sreedher; Vemu, Jahnavi; Boni, Sathoshini; Mailavaram, Raghu Prasad Medicinal Chemistry Research, 2013 , vol. 22, # 3 p. 1090 - 1101

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被引用次数: 7

摘要

Abstract Treatment of 6-alkyl-1-phenyl-4-chloro-(1 H)-pyrazolo [3, 4-d] pyrimidines, with different amines afforded a series of compounds whose identity and purity were confirmed by spectral and analytical means. The compounds were tested for antibacterial activity against four organisms viz. Staphylococcus aureus (Gram positive), S. epidermidis (Gram positive), Bacillus subtilis (Gram positive), Escherichia coli (Gram negative) using ...

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