A new method for generation and intramolecular diels-alder reaction of N-acyl and N-alkoxycarbonyl-1-aza-1, 3-butadibnes. A one-pot synthesis of 1, 7, 8, 8a- …
Abstract A one-pot transformation, made up of i) generation of N-trimethylsilylaldimines from α, β-unsaturated aldehyde, ii) exchange of the silyl group by acyl and oxycarbonyl groups, and iii) intramolecular Diels-Alder reaction of the resulting ψ', ω'-unsaturated N-acyl-and a related N-oxycarbonyl-1-aza-1-3-butadienes in boiling xylene, gave 1, 7, 8, 8a-tetrahydro-3 (2H)-indolizinones (5), the 2-oxa derivatives of 5, and 1, 2, 3, 8, 9, 9a-hexahydro-4 (4H)- ...
