Tetrahedron

Remote stereocontrol by sulfinyl groups: asymmetric alkylation of chiral 2-p-tolylsulfinyl benzyl carbanions

JLG Ruano, MT Aranda, M Puente

文献索引：Garcia Ruano, Jose L.; Aranda, M. Teresa; Puente, Margarita Tetrahedron, 2005 , vol. 61, # 42 p. 10099 - 10104

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被引用次数: 13

摘要

Alkylation reactions of the benzyllithiums derived from enantiomerically pure 2-p-tolylsulfinyl alkylbenzenes have been carried out with excellent yields and high de. A lithiation- substitution sequence, stereochemically controlled by a remote sulfoxide, accounts for the experimental results.