Aromatic sulfide inhibitors of histone deacetylase based on arylsulfinyl-2, 4-hexadienoic acid hydroxyamides
CM Marson, P Savy, AS Rioja…
文献索引：Cass, Quezia B.; Jaxa-Chamiec, Albert A.; Kunec, Ellen K.; Sammes, Peter G. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1991 , # 11 p. 2683 - 2686
... Journal of Medicinal ... MeOH; (d) LiAlH 4 , THF; (e) pyridine−SO 3 , Et 3 N, DMSO; (f) Ph 3 P CHCO 2 Et, CH 2 Cl 2 ; (g) 50% aqueous ... In the quest for a more druglike compound (Scheme 4), a fused system, benzo[b]thiophene, was considered in which a methyl group in the chain ...
