Synthesis of spiro-compounds: use of diselenoacetals for generation of quaternary centres by alkylation and radical cyclization

L Set, DR Cheshire, DLJ Clive

文献索引：Set, Lu; Cheshire, David R.; Clive, Derrick L. J. Journal of the Chemical Society, Chemical Communications, 1985 , # 17 p. 1205 - 1207

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被引用次数: 13

摘要

Ketones are readily converted viathe corresponding diphenyl diselenoacetals (2) into selenides (5) which undergo radical 5-exo cyclization to spiro-compounds (7) on treatment with triphenyltin hydride and azoisobutyronitrile; an analogous sequence serves for the preparation of spiro-lactones (12).