Tetrahedron letters

Mild, effective and selective method for the silylation of alcohols using silazanes promoted by catalytic tetrabutylammonium fluoride

Y Tanabe, M Murakami, K Kitaichi, Y Yoshida

文献索引：Tanabe, Yoo; Murakami, Masanari; Kitaichi, Kazuto; Yoshida, Yoshihiro Tetrahedron Letters, 1994 , vol. 35, # 45 p. 8409 - 8412

全文：HTML全文

被引用次数: 60

摘要

Abstract The presence of catalytic amounts (∼ 0.02 equiv.) of tetrabutylammonium fluoride (TBAF) significantly promoted the silylation of alcohols using a variety of available silazanes under mild conditions with high chemoselectivity, wherein the choice of silazanes allowed an alternative method for the powerful silylation of various kinds of alcohols or the highly regioselective silylation of primary alcohols.