Efficient and chemoselective protection of alcohols and phenols with tert-butyldimethylchlorosilane (TBDMCS) under solvent-free conditions

H Firouzabadi, S Etemadi, B Karimi…

文献索引：Firouzabadi, Habib; Etemadi, Shahrad; Karimi, Babak; Jarrahpour, Ali Asghar Phosphorus, Sulfur and Silicon and Related Elements, 1998 , vol. 143, p. 45 - 51

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被引用次数: 5

摘要

Abstract Various types of primary and secondary alcohols and phenols can be converted efficiently to their corresponding TBDMS ethers using TBDMCS/imidazole under solvent-free conditions. Elimination of DMF, accompanied with an easy non-aqueous work-up and a high rate enhancement of the reaction are worthy to be mentioned for the presented method. The reactions show absolute chemoselectivity for the protection of primary in the presence of ...