Stereoselective hydrogen bromide-promoted hydrogenation of an α-hydroxyoxime

…, JF Marcoux, L Matty, J Wu, D Hughes, PJ Reider

文献索引：Davies; Taylor; Marcoux; Matty; Wu; Hughes; Reider Tetrahedron Letters, 2000 , vol. 41, # 42 p. 8021 - 8025

全文：HTML全文

被引用次数: 16

摘要

One of the most 'atom-economical' means of preparing an amine is hydrogenation of an oxime where the only by-product is water. 7 The hydrogenation of indane-derived keto- or hydroxy-oximes has been known for almost four decades. 8 The cis-aminoindanols are formed in acidic media 9 whereas the trans isomers are formed predominantly in neutral or alkaline solution. Cis-aminochromanol 1 might also be accessible via reduction of the ...