Letters in Organic Chemistry

A Versatile and Efficient Cu-Catalyzed N-Arylation of Aromatic Cyclic Secondary Amines with Aryl Halides

H Yang, Z Miao, R Chen

文献索引：Yang, Haitao; Miao, Zhiwei; Chen, Ruyu Letters in Organic Chemistry, 2011 , vol. 8, # 5 p. 325 - 331

全文：HTML全文

被引用次数: 0

摘要

Aryl-functionalized N-heterocyclic moieties play important roles in organic synthesis, pharmaceutical, or biological areas [1]. The most practical methods in synthesizing arylated N-heterocycle compounds are classic Ullmann-type coupling reactions [2]. Copper catalyzed Ullmann coupling is recognized as one of the most common synthetic protocols for their preparation [3]. However, these methods suffer from the harsh reaction conditions such as high ...