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Development of structure—Activity trends in the series of 3-phenoxychromone derivatives

SA Vasil'ev, VL Boyarchuk, MS Luk'yanchikov…

文献索引:Vasil'ev, S. A.; Boyarchuk, V. L.; Luk'yanchikov, M. S.; Khilya, V. P. Pharmaceutical Chemistry Journal, 1991 , vol. 25, # 11 p. 816 - 821 Khimiko-Farmatsevticheskii Zhurnal, 1991 , vol. 25, # 11 p. 50 - 55

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摘要

7he PHR spectra (Table i) characterize the different positions of the substituents in the phenol part of the ketones (I). Ihe OH groups occur at the position 2 (12.3-11.6 ppm) and 4 (10.7-9.5 ppm) of the phenol part of the moelcule, the aromatic protons of which form an ABX spin system with the Js, 6 of 8 Hz and the J~, 5 of 2 Hz; this corresponds with the coupling constants of the protons in the o-and m-positions. The signal of the 6-H proton is ...

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