α-Aminoamides as ligands in Goldberg amidations

…, MM Hansen, ME Laurila, SP Kolis, JR Martinelli

文献索引：Mitra, Aurpon W.; Hansen, Marvin M.; Laurila, Michael E.; Kolis, Stanley P.; Martinelli, Joseph R. Tetrahedron Letters, 2013 , vol. 54, # 48 p. 6580 - 6583

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被引用次数: 5

摘要

Abstract α-Aminoamides are shown to be useful as ligands in Goldberg amidations. A number of α-aminoamides are examined and the importance of substitution on the α- aminoamides is explored. Acetamide is focused on as the nucleophilic coupling partner due to its low cost, stability and convenience as a protecting group. The initial substrate scope for these catalysts is explored and includes electronically activated and deactivated aryl ...