Synthesis of triazole nucleoside derivatives

Z Li, S Chen, N Jiang, G Cui

文献索引：Li, Zicheng; Chen, Shuhua; Jiang, Ning; Cui, Gang Nucleosides, Nucleotides and Nucleic Acids, 2003 , vol. 22, # 4 p. 419 - 435

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被引用次数: 9

摘要

Abstract 5′-O-Mesyl-2′, 3′-O-isopropylidene ribonucleosides (4 and 12) were converted to their 5′-substituted nucleosides in good yields by reacted with NaN3 or KI. 2′, 3′-O- Isopropylidene ribonucleosides (3 and 11) were prepared in good yields from ribonucleosides 1 and 2 with a reaction mixture of acetone and triethyl orthoformate instead of using acetone diethyl acetal. Compound 1 or 2 was treated with 2-acetoxyisobutyryl ...