Tetrahedron letters

[1, 3] Sigmatropic rearrangement of ketene silyl acetals derived from benzyl α-substituted propanoates

I Shiina, H Nagasue

文献索引：Shiina, Isamu; Nagasue, Hiroshi Tetrahedron Letters, 2002 , vol. 43, # 33 p. 5837 - 5840

全文：HTML全文

被引用次数: 13

摘要

A novel [1, 3] sigmatropic rearrangement of ketene silyl acetals derived from benzyl α- substituted propanoates is developed. The reaction of ketene silyl acetal derived from optically active 1-phenylethyl 2-methylpropanoate mainly proceeds with the retention of chirality at the benzyl position to give the corresponding optically active silyl ester under thermodynamic conditions.