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Journal of the American Chemical Society

Metalated carboxylic acids. I. Alkylation

PL Creger

文献索引:Creger,P.L. Journal of the American Chemical Society, 1967 , vol. 89, # 10 p. 2500 - 2501

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被引用次数: 130

摘要

Aliphatic carboxylic acids and their salts have not been reported to metalate by a simple, generalized process on treatment with Grignard reagents, organolithium reagent^,^,^ or alkali metal amide^.^ Except for salts of acetic acid4* and methacrylic acid, 4b homologous metalated carboxylic acid salts apparently decompose under conditions used for their formation. 4a Arylacetic acids, as well as their salts and simple carboxyl derivatives, are ...