Configuration and preferential solid-state conformations of perindoprilat (S-9780). Comparison with the crystal structures of other ACE inhibitors and conclusions …
…, J Guilhem, M Vincent, G Remond…
文献索引：Pascard; Guilhem; Vincent; Remond; Portevin; Laubie Journal of Medicinal Chemistry, 1991 , vol. 34, # 2 p. 663 - 669
The conformation of perindoprilat, an antihypertensive drug, is studied in the solid state by X- ray analysis. The resolution of its structure reveals important analogies between its observed conformation and that of several ACE inhibitors of the same family. This comparison points out a constant relative orientation of the functional groups, regardless of the molecular environment. This angular constancy appears to us as not being accidental and is a good ...
