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Highly efficient asymmetric direct stoichiometric aldol reactions on/in water

…, X Zhang, DW Armstrong

文献索引:Huang, Junmin; Zhang, Xiaotong; Armstrong, Daniel W. Angewandte Chemie - International Edition, 2007 , vol. 46, # 47 p. 9073 - 9077

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被引用次数: 158

摘要

Many enzymes catalyze reactions in water under mild conditions with high efficiency and excellent stereoselectivity. This highly effective and environmentally benign synthetic methodology is often regarded as a goal in modern organic chemistry.[1] Although enzymes have synthetic utility, they are usually limited by their lack of large-scale compatibility.[2] It is highly desirable to develop a chemical system that can mimic the action of enzymes and ...