Abstract A few novel 3-[5-(4-substituted) phenyl-1, 3, 4-oxadiazole-2-yl]-2-styryl quinazoline- 4 (3 H)-ones were synthesized and evaluated for anticonvulsant, neurotoxicity, sedative- hypnotic, and phenobarbitone-induced hypnosis potentiation test. After ip injection to mice at doses of 30, 100, and 300 mg/kg body weight derivatives were examined in the maximal electroshock-induced seizures (MES) and subcutaneous pentylenetetrazole (scPTZ)- ...
