Naphthoquinone antimalarials. XXIX. 2-Hydroxy-3-(ω-cyclohexylalkyl)-1, 4-naphthoquinones

LF Fieser, JP Schirmer, S Archer…

文献索引：Fieser,L.F. et al. Journal of Medicinal Chemistry, 1967 , vol. 10, p. 513 - 517

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被引用次数: 50

摘要

This investigation is a continuation of work start, ed during World War I1 by the€€ award group. The series cited iri the title has been extended to include members having very large hydrocarbon grolips in the hope that they will undergo metabolic hydroxylation to give products of adequate antimalarial activity in man and resistant to further metabolic oxidat, ion.