One-pot, solvent-free synthesis of α-aminonitriles under catalysis by magnesium bromide ethyl etherate

MM Mojtahedi, MS Abaee…

文献索引：Mojtahedi, Mohammad M.; Abaee, M. Saeed; Abbasi, Hasean Canadian Journal of Chemistry, 2006 , vol. 84, # 3 p. 429 - 432

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被引用次数: 25

摘要

A three-component, efficient, and facile procedure has been developed for the synthesis of α- aminonitriles from aldehydes, amines, and trimethylsilyl cyanide using a catalytic amount of magnesium bromide ethyl etherate in the absence of solvent. Rapid formation of products is observed at room temperature in a one-pot procedure under very mild conditions giving excellent yields of the title compounds. Key words: catalyzed Strecker's reaction, α- ...