Transformed steroids. CXXVII. Synthesis of 16α, 17α-isopropylidenedioxy-pregn-4-en-11β, 21-diol-3, 20-dione, an intermediate product of the preparation of decanide …
AP Krymov, AV Kamernitskii, BI Demchenko…
文献索引：Krymov, A. P.; Kamernitskii, A. V.; Demchenko, B. I.; Vesela, I. V.; Tropina, V. I.; Ioanis'yan, L. I. Pharmaceutical Chemistry Journal, 1983 , vol. 17, # 2 p. 144 - 147 Khimiko-Farmatsevticheskii Zhurnal, 1983 , vol. 17, # 2 p. 200 - 203
Continuing our investigations in this area we studied the behavior of the carbethoxyhydrazone grouping on introducing it into 21-acetoxy-20-ketones and removing it, and we determined the possibility of synthesizing decanide, 16a, 17a- isopropylidenedioxypregna-l, 4-diene-llB, 21-dioi-3, 20-dione, which is a known glucocorticoid preparation with antiinflammatory action [3]. The 21-acetate of 16a, 17a- ...
