A simple and effective preparation of 2-aryl-(or 2-vinyl)-1, 4, 2-oxazaphosphinanes, phosphorus analogues of aryl-morpholinols has been developed, involving palladium catalysed coupling of aryl (or vinyl)-halides with 2-H-1, 4, 2-oxazaphosphinane in presence of triethylamine. A deprotection step was also proposed to afford the corresponding P-aryl-α- aminobenzylphosphinic acid.
