Synthesis and antimicrobial activity of methyl and phenyl diarylmethyl ketones

…, OI Tatarenko, TS Prokhorova, GA Gartman

文献索引：Lapkin, I. I.; Kolbina, N. M.; Tatarenko, O. I.; Prokhorova, T. S.; Gartman, G. A. Pharmaceutical Chemistry Journal, 1987 , vol. 21, # 11 p. 778 - 779 Khimiko-Farmatsevticheskii Zhurnal, 1987 , vol. 21, # 11 p. 1326 - 1328

全文：HTML全文

被引用次数: 0

摘要

General Method of Preparation of Ketones. A 0. i mole portion of propyl lactate or 0. i mole of ethyl mandelate dissolved in ether is added to 0.3 mole of arylmagnesium bromide in ether. After 2 h warming, ethyl formate or AcCl (0.2 mole in each case) is added to the reaction mixture, and the mixture is heated for 2 more h (if ethyl formate is used) or 4 h (if AcCI is added). The subsequent hydrolysis is carried out in 10% HCI. The ether layer is separated ...