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Design, synthesis, structure–activity relationship, and in vivo activity of azabicyclic aryl amides as α7 nicotinic acetylcholine receptor agonists

DP Walker, DG Wishka, DW Piotrowski, S Jia…

文献索引:Bioorganic and Medicinal Chemistry, , vol. 14, # 24 p. 8219 - 8248

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被引用次数: 81

摘要

... page. Bioorganic & Medicinal Chemistry. ... schizophrenia. Interest in the α7 nAChR as a medicinal chemistry target has greatly expanded over the past decade, with a focus on the identification of new and selective chemical entities. ... 2. Chemistry. According ...