Directed lithiation of 4??halopyridines: Chemoselectivity, regioselectivity and application to synthesis

F Marsais, F Trécourt, P Bréant…

文献索引：Journal of Heterocyclic Chemistry, , vol. 25, p. 81 - 87

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被引用次数: 50

摘要

... J. Heterocyclic Chem., 25, 81 (1988). 81 Metalation [1] of pi-deficient heterocycles (pyridine, quinoline ...) has been masked for a while by numerous competitive reactions [2], which generally result from nu- cleophilic attacks on these low LUMO-level aromatics. ...