Molecules

Synthesis and Cyclizations of N-(2, 3-, 3, 4-and 3, 5-Dimethylphenyl)-β-alanines

R Vaickelioniene, V Mickevicius, G Mikulskiene

文献索引：Vaickelioniene, Rita; Mickevicius, Vytautas; Mikulskiene, Gema Molecules, 2005 , vol. 10, # 2 p. 407 - 416

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被引用次数: 10

摘要

Abstract: A series of 1-aryl substituted dihydro-, 5-methyldihydro-and 6-methyl-dihydro-2, 4 (1 H, 3 H) pyrimidinediones and their 2-thio analogues were obtained by reaction of the corresponding β-alanines or α-methyl-and β-methyl-β-alanines with urea or potassium thiocyanate. The reaction of N-(2, 3-and 3, 5-dimethylphenyl)-α-methyl-β-alanines with ethyl acetoacetate gave 1-(2, 3-or 3, 5-dimethylphenyl)-2, 5-dimethyl-1, 4, 5, 6-tetrahydro-4 (1 H ...