Synlett

Regioselective Pd (0)-Catalyzed Hiyama Cross-Coupling Reactions at Dihalo-Substituted Heterocycles

SA Schweizer, T Bach

文献索引：Schweizer, Stefan A.; Bach, Thorsten Synlett, 2010 , # 1 p. 81 - 84

全文：HTML全文

被引用次数: 3

摘要

Abstract The regioselectivity of the Hiyama cross-coupling reaction at various dihalo- substituted heterocycles has been studied. Methyl 2, 3-dibromo-5-furancarboxylate and n- octyltrifluorosilane were employed to find optimum reaction conditions [CsF; Pd 2 dba 3/P (2- furyl) 3 as catalyst, 80-150 C in toluene or benzene] for the desired transformation. Subsequent experiments with the title compounds and with different primary ...