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SAR analysis of innovative selective small molecule antagonists of sphingosine-1-phosphate 4 (S1P 4) receptor

M Urbano, M Guerrero, J Zhao, S Velaparthi…

文献索引:Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 18 p. 5470 - 5474

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被引用次数: 14

摘要

... Bioorganic & Medicinal Chemistry Letters. ... 18 Thus, our chemistry efforts were successively focused on the SAR analysis of the central moiety B with the aim to acquire more insight into the receptor binding mode and identify new chemotypes to address potential metabolic and ...