Chemistry Letters

A green, facile, and one-pot synthesis of 2, 4-(1H, 3H)-quinazolinediones under microwave irradiations

F Nikpour, T Paibast

文献索引：Nikpour, Farzad; Paibast, Touraj Chemistry Letters, 2005 , vol. 34, # 10 p. 1438 - 1439

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被引用次数: 20

摘要

Quinazoline-2, 4-diones are of considerable interest due to their wide pharmacological properties. Here, we have described an environmentally friendly method for the one-pot synthesis of 2, 4-(1H, 3H)-quinazolinediones from the reaction of anthranilic acid derivatives with urea in H 2 O media under microwave irradiations. This method is simple, safe, and fast which produces high yield of products without use of any catalyst.