Tetrahedron letters

Aminoborohydrides. 9. Selective reductions of aldehydes, ketones, esters, and epoxides in the presence of a nitrile using Lithium N, N-dialkylaminoborohydrides

…, GB Fisher, A Reem, CT Goralski, B Singaram

文献索引：Collins, Christopher J.; Fisher, Gary B.; Reem, Adeena; Goralski, Christian T.; Singaram, Bakthan Tetrahedron Letters, 1997 , vol. 38, # 4 p. 529 - 532

全文：HTML全文

被引用次数: 30

摘要

A series of competitive reductions of several functional groups was carried out in the presence of aromatic and aliphatic nitriles using Lithium N, N-dimethylaminoborohydride (LiMe2NBH3) or Lithium Pyrrolidinoborohydride (LiPyrrBH3) as the reducing agents. Both LiMe2NBH3 and LiPyrrBH3 cleanly and quantitatively reduced aldehydes, ketones, esters, and epoxides in the presence of the nitriles to give the corresponding reduction products ...