Solid??phase synthesis of oligodeoxynucleotides containing 4??alkoxythymidine residues
H Roelen, HF Brugghe, H van den Elst…
文献索引：Roelen, H. C. P. F.; Brugghe, H. F.; Elst, H. van den; Marel, G. A. van der; Boom, J. H. van Recueil des Travaux Chimiques des Pays-Bas, 1992 , vol. 111, # 2 p. 99 - 104
Abstract Immobilized and fully protected oligodeoxynucleotides containing a 4-(1, 2, 4- triazolyl)-thymidine residue at a predetermined position were prepared according to a well- established phosphite triester methodology using 2-cyanoethyl phosphoramidites of a 4-(1, 2, 4-triazolyl)-substituted thymidine and standard protected nucleosides. Treatment of the immobilized oligomer with methanol, ethanol or n-propanol in the presence of DBU at 50 ...
