Convenient intermediates for the preparation of C-4 modified derivatives of pyrimidine nucleosides

A Miah, CB Reese, Q Song

文献索引：Miah, Anwar; Reese, Colin B.; Song, Quanlai Nucleosides and Nucleotides, 1997 , vol. 16, # 1-2 p. 53 - 65

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被引用次数: 28

摘要

Abstract 4-(4-Nitrophenoxy)-1-(βD-ribofuranosyl) pyrimidin-2 (1 H)-one 15, 5-methyl-4-(1, 2, 4-triazol-1-yl)-1-(βD-2-deoxyribofu-nosyl) pyrimidin-2 (1 H)-one 7a and 4-(4-nitro-phenoxy)- 1-(β-D-2-deoxyribofurnosyl) pyrimidin-2 (1 H)-one 17a, respectively, have been prepared and are recommended as reactive intermediates for the preparation of derivatives of uridine, thymidine and 2′-deoxyuridine which are modified at C-4.