Synlett

Chemoselective and practical deprotection of alkyl trialkylsilyl ethers in the presence of aryl trialkylsilyl ethers by a catalytic amount of Sc (OTf) 3

T Oriyama, Y Kobayashi, K Noda

文献索引：Oriyama, Takeshi; Kobayashi, Yoshinobu; Noda, Kojiro Synlett, 1998 , # 10 p. 1047 - 1048

全文：HTML全文

被引用次数: 39

摘要

Abstract: Treatment of alkyl trialkylsilyl ethers with 0.5 mol% of Sc (OTf) 3 combined with 5 equivalents of water in acetonitrile provides an efficient and practical method for the deprotection of silyl ethers. Alcoholic trialkylsilyl ethers have been cleaved selectively in the presence of phenolic trialkylsilyl ethers.