Asymmetric Transfer Hydrogenation of Aromatic Ketones Using Rhodium Complexes of Chiral N??Heterocyclic Carbenes Derived from (S)??Pyroglutamic Acid

…, C Bournaud, G Vo??Thanh

文献索引：Aupoix, Audrey; Bournaud, Chloee; Vo-Thanh, Giang European Journal of Organic Chemistry, 2011 , # 15 p. 2772 - 2776

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被引用次数: 15

摘要

Abstract A new and flexible procedure for the preparation of chiral azolium salts derived from (S)-pyroglutamic acid has been developed. The efficiency of these ligands has been evaluated in the metal-catalyzed asymmetric transfer hydrogenation of aromatic ketones in isopropanol. Good enantioselectivities up to 90% ee were observed.