Catalyst??Free Protocol for the Synthesis of Quinoxalines and Pyrazines in PEG

TQ Huang, WY Qu, JC Ding, MC Liu…

文献索引：Huang, Tie-Qiang; Qu, Wen-Yan; Ding, Jin-Chang; Liu, Miao-Chang; Wu, Hua-Yue; Chen, Jiu-Xi Journal of Heterocyclic Chemistry, 2013 , vol. 50, # 2 p. 293 - 297

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被引用次数: 3

摘要

Abstract A facile and simple catalyst-free protocol has been developed for the condensation of 1, 2-diketones with aromatic 1, 2-diamines in polyethylene glycol (PEG), providing quinoxaline derivatives in good yields. The important features of the methodology are broad substrates scope, simple workup, catalyst free, environmentally benign, and no requirement for metal catalysts. It is noteworthy that the cyclization reaction of 1, 2-diketones with ...