Synthesis, topoisomerase I inhibition and structure–activity relationship study of 2, 4, 6-trisubstituted pyridine derivatives

LX Zhao, YS Moon, A Basnet, E Kim, Y Jahng…

文献索引：Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 5 p. 1333 - 1337

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被引用次数: 84

摘要

... Bioorganic & Medicinal Chemistry Letters. ... 1 In addition to such a complexation ability to act as a terdentate, its binding ability to DNA also attracted biologists and medicinal chemists as a potential anticancer agent. ... 2. Chemistry. ...