Synthesis of 1-((S)-3-acetylthio-2-methylpropanoyl)-L-propyl-L-phenylalanine (alacepril) and one of its active metabolites, the desacetyl derivative (DU-1227).
澤山忠弘， 糸川彰， 嶋田莞爾， 土居康正…
文献索引：Chemical and Pharmaceutical Bulletin, , vol. 38, # 2 p. 529 - 531
... 1 and 2 is shown in Chart 1. N—Formylation of proline in peptide chemistry has been ... HzSO4 d) (R)-CH3COSCH2CH(CH3)COCI, KZCO3 e) NH4OH Chart 1 1990 Pharmaceutical Society of ... and chemical shifts are presented only for the trans conformer as the major component. ...
