Improved Synthesis of 2??Hydroxy??4, 4, 6??Trimethyl??2, 5??Cyclohexadienone, Useful as a Flavoring Additive

LD Buyck, Y Zi??Peng, R Verhé…

文献索引：Buyck, Laurent de; Zi-Peng, Yao; Verhe, Roland; Kimpe, De Norbert; Schamp, Niceas Bulletin des Societes Chimiques Belges, 1985 , vol. 94, # 1 p. 75 - 80

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被引用次数: 3

摘要

Abstract The title dienone 1, useful for modification, improvement or increasing organoleptic properties of tobacco, sucrose syrups, flavored beverages, was prepared in 40–558 overall yield from isophorone, by chlorination of 2-hydroxy-isophorone (2), rearrangement into 6- chloro-2-hydroxyisophorone (5) and de-hydrochlorination. An excellent yield of 3-chloro-2- hydroxy-4, 4, 6-trimethyl-2, 5-cyclohexenone (12) was obtained by chlorination of 5 ...