Tetrahedron Letters

Ligand free open air copper (II) mediated aryl formamidation and amination of aryl halides

R Komati, BS Jursic

文献索引：Komati, Rajesh; Jursic, Branko S. Tetrahedron Letters, 2014 , vol. 55, # 9 p. 1523 - 1527

全文：HTML全文

被引用次数: 1

摘要

Abstract A simple synthetic procedure for direct formamidation and amination of aryl halides mediated by copper (II) salts was developed in open air, without an external ligand in formamide with potassium carbonate as a base. This approach is particularly efficient when electron active aryl halides are used as substrates. In these cases almost quantitative formamidation was observed.