Angewandte Chemie International Edition

A Boron??Based Synthesis of the Natural Product (+)??trans??Dihydrolycoricidine

SL Poe, JP Morken

文献索引：Poe, Sarah L.; Morken, James P. Angewandte Chemie - International Edition, 2011 , vol. 50, # 18 p. 4189 - 4192

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被引用次数: 18

摘要

Despite their potential for clinical use many of these compounds are found in low natural abundance; whereas narciclasine (1) is available in practical quantities,[1a, 3] the limited availability of lycoricidine (2), pancratistatin (3), and other derivatives poses one limitation to their development as viable therapeutic agents. Unsurprisingly, the limited availability of these isocarbostyrils, as well as their interesting frameworks, have made these attractive ...