The facile access to 3-and 3, 4-bis (2-cyanoethylsulfanyl) thiophenes allows the straightforward synthesis of 3-alkylsulfanyl and symmetrical or unsymmetrical 3, 4- dialkylsulfanylthiophenes by using a methodology based on a highly efficient sequence of deprotection/alkylation reactions of thiolate group (s).
